Laboratorio I



Línea de Investigación: “Enfermedad de Chagas y Leishmaniasis”

Equipo de Investigación:

Prof. Dra. Patricia Paglini

Dr. Walter Rivarola

Dra. Silvina Lo Presti – Investigadora Asistente de CONICET.

Biol. Alejandra Báez – Becaria Doctoral de Secyt-UNC.

Biol. Carolina Bazán – Becaria Doctoral de CONICET.

Biol. Mariana Strauss – Becaria Doctoral de CONICET.

Méd. Noemí Miller

Méd. Bruno Selva

Dr. Gustavo Guzmán Mentesana

Dra. Romina Blasco – Becaria PROMED.

Dra. Jesica Dimmer – Becaria Post Doctoral de Secyt-UNC

Biol. Camila Barrionuevo – Becaria Doctoral de CONICET

Lic. Blanca Esteves

Pasante Gisele Miana

Est. Noel Reynoso

Est. Diego Moya

Est. Malena Liberal


Gobbi P, Baez A, Lo Presti MS, Enders J,  Fernández A, Fretes R, Paglini-Oliva P, Rivarola W. Association of clomipramine and allopurinol for the treatment of the experimental infection with T. cruzi Parasitol Res. . 107(5):1279-1283.; 2010.

Micussi LR, Bazán PC, Fauro R, Baez A, Lo Presti MS, Triquell MF, Paglini P, Rivarola HW. Importance of host sex in the development of Trypanosome cruzi infection. Rev Fac Cien Med Univ Nac Córdoba 67: 69-72; 2010.

Guzman Mentesana G, Baez A, Córdoba R, Dominguez R, Lo Presti S, Rivarola W, Pons P, Fretes R, Paglini-Oliva P .Role of mitochondria and reactive oxygen species in the progression of heart failure..Rev Fac Cien Med Univ Nac Cordoba. ;67(4):150-158. ; 2010.

Baez A, Lo Presti MS, Rivarola HW, Guzman Mentesana G, Pons P, Fretes R, Paglini-OlivaP.  Mitochondrial involvement in the chronic chagasic cardiomiopathy .Trans of the Royal Soc of Trop Med and Hyg . 105: 239-246; 2011.

Relevance in biofilms in pediatric tonsillar disease.  Diaz RR, Picciafuoco S, Paraje MG, Villegas NA, Miranda JA, Albesa I, Cremonezzi D, Commisso R, Paglini-Oliva P.Eur J Clin Microbiol Infect Dis.  30: 1503-1509; 2011.

Rivarola HW, Patricia Paglini-Oliva. New insights into pathophysiology and treatment in Chagas-Mazza disease.Rev Fac Cien Med Univ Nac Cordoba. 68: 154-163; 2011.

Díaz-Luján C,  Triquell MF , Schijman A , Paglini P ,Fretes R Differential susceptibility of isolated human trophoblasts to infection by Trypanosoma cruzi. Placenta 33: 264-270; 2012.

Bigliani MC, Rossetti V, Grondona E, Presti SL, Paglini PM, Rivero V, Zunino MP, Ponce AA. Chemical compositions and properties of Schinus areira L. essential oil on airway inflammation and cardiovascular system of mice and rabbits. Food Chem Toxicol. 50: 2282-2288; 2012.

Bazan C, Micucci l , Fauro R , Triquel M.F , Lo Presti M.S, Baez A, Strauss M, Camino G, Paglini-Oliva Patricia, Rivarola H.W.Persistence of Trypanosoma cruzi in Experimental Chagasic Cardiomyopathy.  Anti Infective Ag 10:136-141; 2012.

Baez A, Lo Presti MS, Rivarola HW,  Pons P, Fretes R, Paglini-Oliva P. Chronic indeterminate phase of Chagas’ disease: mitochondrial involvement in infection with two strains. Parasitology 140: 414-421; 2013.

Fauro R, Lo  Presti, Bazán C, Baez A, Strauss M,Triquell F, Cremonezzi D,  Sanchez Negrete O,  Camino Willhuber G, Paglini- Oliva and Rivarola HW. Use of clomipramine as chemotherapy of the chronic phase of Chagas disease. Parasitology :140, 917-27.  2013.

Strauss, M. Lo Presti S, Bazán C, Baez A, Fauro R,  Esteves B, Sanchez Negrete O, Cremonezzi D, Paglini-Oliva P, Rivarola HW. Clomipramine and benznidazole association for the treatment of acute experimental Trypanosoma cruzi infection. Parasitology International 62:293-9;  2013.

Guzman Mentesana G, Baez A , Lo Presti MS,, Dominguez R, Córdoba R, Rivarola HW, Fretes R,  Paglini-Oliva P.Functional and structural alterations of cardiac and skeletal muscle mitochondria  in heart failure patients . Arch. Med Res. 45: 237-246; 2014.

Lo Presti S, Esteves B, Moya D, Bazan PC, Strauss M, Baez A, Pizzi R, Quispe Recalde MA, Valladares B, Rivarola W, Paglini-Oliva P.  Circulating Trypanosoma cruzi populations differ from those found in the tissues of the   same host during acute experimental infection. Acta Tropica. 133:98-109; 2014.

Lo Presti MSBazán PCStrauss MBáez ALRivarola HWPaglini-Oliva PA    Trypanothione reductase inhibitors: Overview of the action of thioridazine in different stages of Chagas disease. Acta Tropica. 145:79-87; 2015.

Báez ALReinoso MNLo Presti MSBazán PCStrauss MMiler NPons PRivarola HWPaglini-Oliva P. Mitochondrial dysfunction in skeletal muscle during experimental Chagas disease. Exp Mol Pathol. 98: 467-475; 2015.

Capítulos de Libros

Electrocardiography as a Diagnostic Method for Chagas Disease in Patients and Experimental Models. Patricia Paglini_Oliva, M Silvina Lo Prest and H Walter Rivarola. In Parasitology, In Tech,  2012.

Antidepressants Used as Chemotherapy for Trypanosoma cruzi Infection: Phenothiazines and Related Compounds .Paglini Oliva P, Lo Presti S, Rivarola R. Frontiers in Anti-Infective Drug Discovery. Betham Science  e-books. 2015.